Studies are showing that one in five males have low testosterone under the age of 40.
In younger males, or more mature males with function testes, Human Chorionic Gonadotropin (HCG) is the preferred treatment to raise testosterone. Testosterone injections should not be used, unless there is failure of the testicles to produce testosterone with the use of HCG, especially in younger men.
HCG is a protein-based hormone with an alpha and a beta sub-unit. The alpha sub-unit is almost identical to the alpha sub-units of Luteinizing Hormone, the signal from the brain to produce more testosterone, and Follicular Stimulating Hormone, the signal from the brain to produce more sperm. For this reason, HCG stimulates the testicles in a manner like Luteinizing Hormone (LH), the signal from the brain to the testes to produce more testosterone.
The advantage of using HCG in younger males is that you get no loss of testicle volume and no decrease in sperm count that you get with testosterone replacement treatment, such as injections of testosterone, testosterone patches, gels or creams, and testosterone pellets.
Antibodies can develop with use, so most protocols suggest using HCG two months on and one month off. Total, free, and bio-available testosterone usually increases about 25% and symptoms of testosterone deficiency are improved.