MDLifespan, a leader in therapeutic plasma exchange (TPE), is expanding its reach with new centers opening in Michigan, Florida, and Texas in 2025, with additional locations planned to follow nationwide.
The expansion introduces MDLifespan’s suite of Advanced TPE protocols, addressing areas including brain health, heart health, immune support, cancer-related health goals, prenatal wellness, and longevity.
Environmental toxins—including microplastics, PFAS, toxic metals, and other contaminants—are increasingly recognized as important areas of environmental health research. These substances can enter the body through food, air, water, consumer products, and other sources, while research continues to examine their potential relationships with inflammation, oxidative stress, and long-term health.
According to toxin expert Dr. Paul Savage, founder of MDLifespan, “We are living in an era where toxin exposure has escalated dramatically, doubling every decade for the past 60 years. This cumulative burden blocks healing, accelerates aging, and fuels all chronic inflammatory diseases.”
MDLifespan’s approach is rooted in Advanced Serial Therapeutic Plasma Exchange, a physician-led approach built around therapeutic plasma exchange, personalized diagnostics, biomarker tracking, and supportive therapies. The goal is to help reduce circulating toxin burden and inflammatory compounds while supporting individualized health and wellness plans.
Therapeutic plasma exchange has been used in clinical settings for decades. MDLifespan’s Advanced TPE approach applies the procedure within personalized protocols that incorporate diagnostic testing and additional supportive strategies.
MDLifespan combines therapeutic plasma exchange with personalized diagnostics, nutrient support, and other supportive therapies within its Advanced TPE protocols.
During therapeutic plasma exchange, plasma is separated from blood cells and exchanged with replacement fluid such as albumin. This established procedure can help remove substances circulating in plasma. MDLifespan incorporates the procedure into physician-led protocols designed around individual health goals and biomarker data.
The approach is intended to provide a structured framework for evaluating toxin burden, monitoring biomarkers, and supporting individualized health optimization.
MDLifespan’s approach is rooted in data, disease context, and detection. Advanced diagnostics are used to evaluate relevant biomarkers and toxin levels, while pre- and post-protocol testing can help track changes over time.
“Our goal is to empower patients with actionable insights and transformative outcomes,” says Dr. Paul Savage, founder of MDLifespan. “By focusing on the removal of harmful toxins and tracking real-time health improvements, we’re setting a new standard in personalized medicine.”
MDLifespan’s Advanced TPE protocols are designed around specific health goals and individual patient considerations.
Every protocol is supported by pre- and post-protocol laboratory testing where appropriate to help track biomarkers and provide data for ongoing physician-guided planning.
MDLifespan’s 2025 expansion was designed to bring physician-led therapeutic plasma exchange and Advanced TPE protocols to more communities across the United States, with new centers planned in Michigan, Florida, and Texas and additional locations expected to follow.
MDLifespan’s nationwide location network has since expanded to multiple markets, including Florida and Texas, giving prospective patients more opportunities to learn about physician-led Advanced TPE in their region.
For patients interested in understanding the approach, MDLifespan provides information about Advanced Serial Therapeutic Plasma Exchange, its protocols, locations, and physician consultation process.
Environmental toxin exposure remains an important area of public-health and scientific research. Research has documented the presence of microplastics in drinking water, while federal health agencies continue to evaluate the potential health effects associated with PFAS exposure.
At the time of this announcement, MDLifespan reported more than 300 successful PlasmaXchange procedures performed to date as part of its development of personalized Advanced TPE protocols.
“This is more than a medical breakthrough; it’s a movement,” Dr. Savage states. “Our goal is to empower individuals to protect their health in an increasingly toxic world and discover what we can do with patients already beset by chronic inflammatory diseases.”
MDLifespan will celebrate its expansion with virtual and in-person events, offering consultations, webinars, and exclusive promotions to introduce its protocols to new communities.
For more information about Advanced Serial Therapeutic Plasma Exchange and MDLifespan’s approach, visit MDLifespan’s Advanced Serial Therapeutic Plasma Exchange resource.
To learn more about environmental toxin exposure and practical ways to reduce everyday exposures, explore MDLifespan’s Avoiding Toxins resource.
Originally published March 31, 2025. Republished in the MDLifespan Newsroom.
Jessica Rafaeil is a journalist and wellness writer specializing in therapeutic plasma exchange, sleep, nutrition, and alternative medicine. With over eight years of experience covering health trends, she has contributed to publications such as US Black Engineer and IT, Women of Color, Hispanic Engineer, Digital Journal, and Sway’s Universe. Jessica combines journalism with branding expertise to elevate the voices of health-focused brands while advocating for diversity and inclusion in media.