Plasma Exchange
Plasmapheresis for Alzheimer's Disease
Alzheimer’s disease progression is driven by the accumulation of toxic beta-amyloid proteins, inflammatory cytokines, and vascular transport impairments in the bloodstream and brain. Personalized plasmapheresis mechanically removes these disease-driving proteins while replacing them with antioxidant-rich therapeutic albumin. By clearing circulating neurotoxins and slowing cognitive decline, plasma exchange can effectively stabilize daily functional abilities.
Schedule a free appointment to find out if plasma exchange can help you.
Topic Quicklinks
AMBAR Study: Slowing Alzheimer's with Plasma Exchange
The landmark Phase 2b/3 AMBAR trial demonstrated that therapeutic plasma exchange with albumin replacement significantly slows cognitive and functional decline in patients with mild-to-moderate Alzheimer’s disease. By mechanically clearing toxic beta-amyloid proteins and inflammatory cytokines from circulation, the protocol achieved up to a 61% reduction in disease progression compared to placebo.
Download the study to find out:
- Complete Clinical Efficacy Data: Detailed breakdowns of cognitive and functional scores (including ADAS-Cog and ADCS-ADL) showing treatment impact across mild and moderate disease stages.
- Biomarker & Clearance Analysis: Insights into how circulating beta-amyloid and inflammatory plasma proteins are mobilized and removed from central nervous system pathways.
- Treatment Protocols & Dosing Schemes: Specific operational details on the 6-week conventional plasma exchange phase followed by the 12-month low-volume maintenance regimen.
- Safety & Tolerability Profiles: Comprehensive safety outcomes, patient compliance rates, and adverse event profiles across all treatment arms.
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Free 30-min Telehealth Appointment
Learn more about plasma exchange and if it can help your cognitive condition or symptoms. Schedule a free 30-minute telehealth appointment.
- Review your history and symptoms to find out if you are a good candidate for therapeutic plasma exchange (TPE).
- Learn how MDLifespan’s unique approach to Advanced Serial Therapeutic Plasma Exchange can be more effective than other methods.
- Determine how to personalize our plasma exchange procedures to your unique goals and history.
- The virtual doctor’s appointment is free. No insurance is required.
Our Personalized Approach to Plasma Exchange
Advanced Serial TPE is a patent pending procedure that can be more effective than traditional plasma exchange.
Personalized Plan
Advanced Serial TPE adds advanced diagnostics, tracks toxin levels & biomarker changes, and uses those results to personalize the plasma exchange plan.
Multi-modal Program
Beyond TPE, Plasma exchange bundles IV nutrient therapy after each session, daily protein-powder supplementation, and lifestyle guidance to enhance TPE effects.
Specialized Physicians
Our physicians specialize in TPE and use their focused experience to design highly individualized plans that account for complex conditions and maximize the removal of disease-causing substances.
Advanced Serial TPE Patient Case Studies
Hear stories from patients who received the Advanced Serial TPE procedures.