June 3, 2026
Written By: 
Dr. Paul Savage
Founder and Chief Medical Officer
Dr. Paul Savage, founder and Chief Medical Officer of MDLifespan, is a pioneer in personalized medicine and toxin reduction. He developed the patent-pending PlasmaXchange™ protocols to address the global toxin crisis by combining therapeutic plasma exchange with patient education, advanced diagnostics, and personalized therapies. A former ER physician who transformed his own health through integrative and lifestyle medicine, Dr. Savage has dedicated his career to revolutionizing healthcare by making regenerative therapies accessible and scalable. Dr. Savage is the founder of BodyLogicMD, host and producer of The TPE Blueprint podcast, and a contributing author to Suzanne Somers’ Ageless. His work has been published in ScienceDirect. As a keynote speaker and educator, he champions toxin elimination, hormone optimization, and longevity medicine.
Learn how MDLifespan approaches Therapeutic Plasma Exchange (TPE) with medical oversight, scientific transparency, and patient safety. A message from Dr. Paul Savage and the MDLifespan Board.
Therapeutic Plasma Exchange (TPE) has emerged as a powerful tool with a wide range of clinical applications in medical advancements. While known for managing various autoimmune diseases and blood disorders, TPE holds immense potential in cancer prevention.
Liquid biopsy has emerged in the past decade as an advanced tool in early cancer detection. Historically, cancer was suspected on a cancer screening test such as a PSA test, Pap smear, mammogram, colonoscopy, or skin exam.
Blood is the conveyor belt of the body. Blood delivers all the supplies to the cells such as oxygen, nutrients, infection fighting cells, and many types of proteins. Blood then removes all the garbage from the cells such as carbon dioxide, breakdown products of metabolism, and toxins.
In the past 30 years, various approaches to healthcare have gained popularity, making it essential for patients to understand the differences between different typesof medical practices. Here is a concise definition and differentiation between Western, anti-aging, integrative, alternative, complementary, and traditional Medicine.
Ask any longevity specialist in the field, “what is the most dangerous condition in the human body?” and 99% of them will say chronic inflammation. Left untreated, chronic inflammation can damage healthy cells and organs.
Cancer is a terrifying and life-threatening disease. Over 600,000 people will die of this horrific disease in the United States this year. Cancer is caused by aging, toxins, radiation, inflammation, oxidation, viruses, or trauma that damages a healthy cell’s DNA.
Think of a biomarker report like looking at the dashboard of a car. A car has gauges that can measure the air pressure of the tires, the amount of gas in the tank, the temperature of the engine, and the quality of the oil in the filter, just to name a few.
In August 2022, a landmark study about the effects of Therapeutic Plasma Exchange (TPE) on the biomarkers of aging grabbed the attention of every longevity researcher and clinician, as well as that of millions of aging adults.