Therapeutic Plasma Exchange (TPE): MDLifespan vs. Our Competitors

At MDLifespan, we are a physician-led, expert team of clinicians focused exclusively on therapeutic plasma exchange (TPE). Our patent pending PlasmaXchangeTM Protocols, which range from three to five treatments, reduce several synthetic chemicals from the body, promoting longevity and reduction of inflammatory markers.

Our clinical study, focused on environmental toxins, found that PlasmaXchangeTM Protocols reduce BPA by 71.5%, phthalates by 75.7% and glyphosate by 68%.

In the increasingly crowded world of therapeutic plasma exchange (TPE), not all plasmapheresis services are created equal. While many clinics dabble in therapeutic plasma exchange (TPE) as one of many offerings, MDLifespan is the only choice for toxin removal by a team of experts dedicated exclusively to PlasmaXchange™.

1. Physician-Led, Not Trend-Led

MDLifespan protocols are developed and overseen by a team of medical advisors, who bring a combined 100-plus years of clinical experience across their respective fields.
Our physician leadership includes:

• Dr. Paul Savage MD – a pioneer in personalized medicine, a physician focused on patients, backed by science
• Dr. Pamela Smith, MD, MPH, MS — internationally acclaimed physician and educator
• A team of board-certified specialists in neurology, cardiology, oncology, and OB/GYN who lend their expertise to protocol design and patient support.
• Every protocol is physician-led, and nurse-executed. All our providers are certified in Personalized Medicine by USF.

2. Evidence-Backed Results & Published Research

MDLifespan has presented our clinical data at national medical conferences and peer-reviewed publications.

• Over 300 successful TPE procedures in the last year.
• PlasmaXchange™ protocols are more effective than TPE alone.
• Overall toxin loads reduced: 71.5% decrease in BPA, 75.7% decrease in phthalates, 68% decrease in glyphosate.
• Backed by the Morsani College of Medicine at the University of South Florida’s Personalized Medicine Program.
• Protocols and results supported by nationally recognized neurologists (Dr. Syed Asad), toxicologists (Dr. Health Joliff, Dr Lyn Patrick), cardiologists (Dr. Chris Davis, Dr. Michael Davidson), OB/GYNs (Dr. Lisa Semple), mold experts (Dr. Jill Carnahan), and dozens more.

3. Personalized Protocols for Every Stage of Life

TPE alone is not a one-size-fits-all approach to wellness. MDLifespan offers patent-pending PlasmaXchange™ Protocols tailored to your specific health needs:

• Heart – Therapeutic plasma exchange decreases levels of routinely used cardiac and inflammatory biomarkers, according to recent research.
• Brain – According to the AMBAR study, plasma exchange with an albumin replacement can slow cognitive and functional decline in mild-to-moderate AD (especially moderate cases), and may associate with less brain volume loss over time.
• Cancer Recovery – Recent studies indicate TPE may help modulate immune surveillance and reduce systemic inflammation, potentially enhancing the effectiveness of other cancer therapies.
• Baby – Dr. Lisa Semple, a board-certified OBGYN, recommends PlasmaXchange™ for optimizing preconception and maternal health. By alleviating the mother of overall toxic burden, her baby can thrive in a prenatal environment with minimal ` the risk of adverse pregnancy outcomes and provide a fresh start from the moment of conception.
• Mold – co-developed with Dr. Jill Carnahan, whose supports PlasmaXchange™ as the one of the most effective ways to remove mold toxins.
• Toxin – MDLifespan’s study of full-body detoxification with serial therapeutic plasma exchange significantly reduces harmful toxins in healthy adults.
• Longevity – The study published demonstrates how plasma exchange increasing telomeres and decreasing inflammation and oxidation.
• Immunity – Research shows TPE can strengthen lymphocytes defense and reset immune balance.

4. Beyond Detox: The MDLifespan Protocol Difference

Our PlasmaXchange Protocols go further than basic TPE. Each includes:

• Advanced diagnostic testing to identify toxins and track biomarker progress.
• Regenerative medicine therapies to accelerate healing and resilience.
• Proprietary supplements and nutrient formulations to enhance the protocol.
• Toxin avoidance guidance to help patients reduce future exposures and maintain long-term benefits.

This comprehensive approach ensures results are not just achievedable — they’re sustainable.

5. The MDLifespan Promise

We are the only PlasmaXchange™ provider that combines:

• 100+ years of combined medical experience
• Leadership by Dr. Paul Savage, Dr. Pamela Smith, and nationally recognized medical advisors
• Published research and peer-reviewed science in progress
• Patent-pending PlasmaXchange™ Protocols (Heart, Brain, Immunity, Baby, Cancer, Mold, Toxin)
• Exclusive focus on advanced therapeutic plasma exchange, toxin removal, and regenerative wellness

MDLifespan isn’t just another TPE clinic. We are setting the gold standard for therapeutic plasma exchange. Schedule your free physician consultation to discover the difference that expertise, personalization, and proven science can make in your health journey.