PlasmaXchange
Therapeutic Plasma Exchange
Certain diseases and environments cause inflammatory proteins, chronic infections, and other toxins to build up in every part of the body and bloodstream. Personalized therapeutic plasma exchange (or plasmapheresis) offers an effective and safe way to help the body eliminate harmful contaminants and strengthen the immune system.
To learn more or get specific pricing, schedule a free 30-min telehealth appointment.
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Plasma Exchange Removes Harmful Substances from Your Body
Therapeutic plasma exchange is a medical procedure that filters out contaminated plasma from the body then combines healthy blood with a new customized saline-albumin-vitamin combination plasma solution. This process gets rid of harmful substances such as autoimmune complexes, toxins, and inflammatory mediators, and helps to reset immune system activity and reduce symptoms caused by diseases.
Plasma exchange helps remove these harmful substances:
- Environmental Toxins: Heavy metals (e.g., Lead, Mercury), Mycotoxins (mold toxins), PFAs, and Persistent Organic Pollutants (POPs) like PCBs, which bind to plasma proteins.
- Alloantibodies: Antibodies produced against foreign antigens, often relevant in transplant rejection or blood incompatibility.
- Immune Complexes (Antigen-Antibody Complexes): Clumps of antigens and antibodies that can circulate and deposit in organs, causing inflammation and damage (e.g., in Vasculitis, Lupus Nephritis).
- Immunoglobulin Paraproteins (M-proteins): Abnormal, monoclonal proteins (like IgG or IgM) produced in diseases such as Multiple Myeloma or Waldenström’s Macroglobulinemia, which can cause hyperviscosity (thick blood).
- Cryoglobulins: Immunoglobulins that clump together at low temperatures, causing vascular issues (e.g., Cryoglobulinemia).
- Inflammatory Cytokines/Mediators: Proteins that drive systemic inflammation.
By removing the contaminated plasma, TPE lowers the concentration of these harmful components in the body, naturally strengthens the immune system, and alleviates the symptoms of various disorders.

Do You Qualify for TPE?
Therapeutic plasma exchange can be powerful but it isn’t the right option for everyone. In order to determine if TPE can be helpful for your unique situation, take the qualification assessment.
- Find out if you qualify for TPE and what protocols may be helpful for your health goals.
- Get educational resources personalized for your health goals.
- Learn what next steps could make sense for you.
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Our Personalized Approach to Plasma Exchange
PlasmaXchange is a patent pending TPE procedure that can be more effective than traditional plasma exchange.
Personalized Plan
PlasmaXchange adds advanced diagnostics, tracks toxin levels & biomarker changes, and uses those results to personalize the plasma exchange plan.
Multi-modal Program
Beyond TPE, PlasmaXchange bundles IV nutrient therapy after each session, daily protein-powder supplementation, and lifestyle guidance to prevent re-toxification.
Specialized Physicians
Our physicians specialize in TPE and use their focused experience to design highly individualized plans that account for complex conditions and maximize the removal of disease-causing substances.
PlasmaXChange Patient Case Studies
Hear stories from patients who received the personalized PlasmaXChange TPE procedure.
PlasmaXchange Pricing
MDLifespan offers a variety of PlasmaXchange protocols designed to address specific health challenges and wellness goals. Each program is personalized to your unique clinical needs, utilizing targeted diagnostics and nutrient therapies to maximize effectiveness for your individual scenario.
Pricing for these programs starts at $5,995. To get a detailed recommendation and specific pricing for your health goals, please schedule a 30-minute appointment with an MDLifespan doctor.
Slide table to the left on mobile
| Protocol Name | Targeted Conditions & Applications | TPE Sessions | IV Nutrient Therapy |
|---|---|---|---|
| MDL Mold | Mold toxicity, CIRS, chronic fatigue, mycotoxin-related brain fog. | 3 or 5 | Dr. Jill Mold Formula |
| MDL Toxin | Heavy metals, pesticides, PFAS (forever chemicals), microplastics. | 3 or 5 | Clean Sweep |
| MDL Immunity | Immunity resilience, autoimmune (Arthritis, MS), Lyme disease, chronic infections, Mast Cell (MCAS). | 3 or 5 | Vital Defence |
| MDL Brain | Alzheimer's, ALS, neuroinflammation, memory loss, brain fog. | 5 | Cognitive Clarity |
| MDL Heart | Systemic inflammation, cardiovascular disease, arterial health. | 5 | Pulse Power |
| MDL Longevity | Slow biological aging, high oxidative stress, high biological age markers, general vitality. | 3 or 5 | Timeless Wellness |
| MDL Cancer | Immune support during recovery, lowering markers tied to progression. | 3 | Cancer Shield |
| MDL Baby | Clearing toxic burden before pregnancy for optimal fetal health. | 2 | Pure Beginnings |
| MDL Basic | Maintenance for healthy individuals, "oil change" for the blood. | 1 – 3 | None |
Each protocol is customized to your specific needs to ensure we maximize effectiveness. By tailoring the number of sessions and the nutrient therapies to your biology, we can more effectively target the root causes of your health concerns. To receive your personalized protocol options and a detailed pricing breakdown, please schedule a 30-min appointment with our doctors.
MDLifespan Locations
We’re bringing the transformative benefits of PlasmaXchange™ to more individuals nationwide.
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| State | City | Address | Phone | Schedule |
|---|---|---|---|---|
| AZ | Mesa | 5949 East University Drive, Mesa, AZ 85205, USA | (844) 752-7629 | Schedule an appointment |
| CA | Beverly Hills | 433 North Camden Drive #560, Beverly Hills, CA 90210, USA | (844) 752-7629 | Schedule an appointment |
| CO | Denver | 400 S McCaslin Blvd suite 210, Louisville, CO 80027, USA | (844) 752-7629 | Schedule an appointment |
| FL | Miami | 1200 Ponce de Leon Boulevard suite 1500, Coral Gables, FL 33134, USA | (844) 752-7629 | Schedule an appointment |
| FL | Tampa | 504 North Reo Street, Tampa, FL 33609, USA | (844) 752-7629 | Schedule an appointment |
| FL | Sarasota | 1990 Main St suite 800, Sarasota, FL, USA | (844) 752-7629 | Schedule an appointment |
| FL | Orlando | 7009 Dr Phillips Blvd #150, Orlando, FL, USA | (844) 752-7629 | Schedule an appointment |
| GA | Atlanta | 2 Ravinia Drive Northeast suite 1210, Atlanta, GA 30346, USA | (844) 752-7629 | Schedule an appointment |
| IL | Chicago | 770 N Halsted St Suite 204, Chicago, IL 60642, USA | (844) 752-7629 | Schedule an appointment |
| MI | Detroit | 1900 S Telegraph Rd suite 100, Bloomfield Township, Michigan, USA | (844) 752-7629 | Schedule an appointment |
| NJ | New York City | 535 E Crescent Ave, Ramsey, NJ 07446, USA | (844) 752-7629 | Schedule an appointment |
| TX | Houston | Magnolia Pharmacy, 18230 FM 1488 #100, Magnolia, TX, USA | (844) 752-7629 | Schedule an appointment |